diff --git a/src/backend/InvenTree/build/serializers.py b/src/backend/InvenTree/build/serializers.py
index e4aba183b6..5aa8d2a701 100644
--- a/src/backend/InvenTree/build/serializers.py
+++ b/src/backend/InvenTree/build/serializers.py
@@ -205,6 +205,10 @@ class BuildSerializer(
 
         super().__init__(*args, **kwargs)
 
+        if self.instance is not None:
+            # The 'part' field cannot be changed once a build order has been created
+            self.fields['part'].read_only = True
+
     @transaction.atomic
     def create(self, validated_data):
         """Create a new Build instance, optionally copying data from an existing build."""
diff --git a/src/backend/InvenTree/build/test_api.py b/src/backend/InvenTree/build/test_api.py
index 8b806e489f..9068f2ce40 100644
--- a/src/backend/InvenTree/build/test_api.py
+++ b/src/backend/InvenTree/build/test_api.py
@@ -202,6 +202,24 @@ class BuildTest(BuildAPITest):
             str(data['outputs'][0]['output']),
         )
 
+    def test_part_read_only_on_update(self):
+        """The 'part' field cannot be changed on an existing build order."""
+        self.assignRole('build.change')
+
+        url = reverse('api-build-detail', kwargs={'pk': self.build.pk})
+
+        other_part = (
+            Part.objects.filter(assembly=True).exclude(pk=self.build.part.pk).first()
+        )
+
+        self.assertIsNotNone(other_part)
+
+        # Attempting to change the 'part' field is silently ignored
+        self.patch(url, {'part': other_part.pk}, expected_code=200)
+
+        self.build.refresh_from_db()
+        self.assertNotEqual(self.build.part.pk, other_part.pk)
+
     def test_complete(self):
         """Test build order completion."""
         # Initially, build should not be able to be completed