diff --git a/InvenTree/part/models.py b/InvenTree/part/models.py
index 35872c09ba..7973e408ce 100644
--- a/InvenTree/part/models.py
+++ b/InvenTree/part/models.py
@@ -779,7 +779,7 @@ class Part(MPTTModel):
 
         # Raise an error if an IPN is set, and it is a duplicate
         if self.IPN and not allow_duplicate_ipn:
-            parts = Part.objects.filter(IPN__iexact=self.IPN)
+            parts = Part.objects.filter(IPN=self.IPN)
             parts = parts.exclude(pk=self.pk)
 
             if parts.exists():
diff --git a/InvenTree/part/test_part.py b/InvenTree/part/test_part.py
index 040b2c9e68..889259d183 100644
--- a/InvenTree/part/test_part.py
+++ b/InvenTree/part/test_part.py
@@ -348,6 +348,26 @@ class PartSettingsTest(TestCase):
         with self.assertRaises(ValidationError):
             part = Part(name='Hello', description='A thing', IPN='IPN123', revision='C')
             part.full_clean()
+        
+        # Any duplicate IPN should raise an error
+        Part.objects.create(name='xyz', revision='1', description='A part', IPN='UNIQUE')
+
+        # Case sensitive, so other variations don't error out:
+        Part.objects.create(name='xyz', revision='2', description='A part', IPN='UNIQUe')
+        Part.objects.create(name='xyz', revision='3', description='A part', IPN='UNIQuE')
+        Part.objects.create(name='xyz', revision='4', description='A part', IPN='UNIqUE')
+
+        with self.assertRaises(ValidationError):
+            Part.objects.create(name='zyx', description='A part', IPN='UNIQUE')
+
+        # However, *blank* / empty IPN values should be allowed, even if duplicates are not
+        # Note that leading / trailling whitespace characters are trimmed, too
+        Part.objects.create(name='abc', revision='1', description='A part', IPN=None)
+        Part.objects.create(name='abc', revision='2', description='A part', IPN='')
+        Part.objects.create(name='abc', revision='3', description='A part', IPN=None)
+        Part.objects.create(name='abc', revision='4', description='A part', IPN='  ')
+        Part.objects.create(name='abc', revision='5', description='A part', IPN='  ')
+        Part.objects.create(name='abc', revision='6', description='A part', IPN=' ')
 
 
 class PartSubscriptionTests(TestCase):